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Image Search Results
Journal: Molecular Biology and Evolution
Article Title: Evolutionary Transition of Promoter and Gene Body DNA Methylation across Invertebrate–Vertebrate Boundary
doi: 10.1093/molbev/msv345
Figure Lengend Snippet: Distribution of DNA methylation in different TE classes of Ciona intestinalis . Only LINEs and SINEs have substantially methylated subsets.
Article Snippet: To directly analyze the patterns of DNA methylation, we used experimentally determined
Techniques: DNA Methylation Assay, Methylation
Journal: Molecular Biology and Evolution
Article Title: Evolutionary Transition of Promoter and Gene Body DNA Methylation across Invertebrate–Vertebrate Boundary
doi: 10.1093/molbev/msv345
Figure Lengend Snippet: ( A ) Distributions of promoter and gene body DNA methylation from whole-genome methylation maps in four species across the chordate phylogeny. Both promoters and gene bodies are composed of lowly (mean fractional methylation level < 0.3) and highly methylated (mean fractional methylation level > 0.5) subsets in these species, and show good correspondence with the CpG O/E values. ( B ) Using empirical cutoff values, the proportions of lowly and highly methylated promoters and gene bodies of the study species are depicted.
Article Snippet: To directly analyze the patterns of DNA methylation, we used experimentally determined
Techniques: DNA Methylation Assay, Methylation
Journal: Molecular Biology and Evolution
Article Title: Evolutionary Transition of Promoter and Gene Body DNA Methylation across Invertebrate–Vertebrate Boundary
doi: 10.1093/molbev/msv345
Figure Lengend Snippet: ( A ) Sea squirt ( Ciona intestinalis ) genes with low and high levels of DNA methylation in promoters and gene bodies. Figures drawn using values calculated from sliding windows that are 100 bases wide with a 10-base step size. Genes in this species can be classified into four groups, where promoter and gene bodies are lowly and highly methylated, respectively. The numbers of genes in each group are described in the main text. ( B ) Variation of gene expression levels of these four methylation categories.
Article Snippet: To directly analyze the patterns of DNA methylation, we used experimentally determined
Techniques: DNA Methylation Assay, Methylation, Gene Expression